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Ketoconazole
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Ketoconazole

Ketoconazole is an imidazole antifungal agent. Ketoconazole has oral tablet, cream and dandruff shampoo formulations. The oral formulation is available in USA since 1981. Ketoconazole is the only member of the imidazole class that is currently used for treatment of systemic infections. Ketoconazole is a highly lipophilic compound. This property leads to high concentrations of Ketoconazole in fatty tissues and purulent exudates. Expectedly, the distribution of Ketoconazole into cerebrospinal fluid is poor even in the presence of inflammation. Its oral absorption and solubility is optimal at acidic gastric pH. While Ketoconazole was more widely used before the development of newer, less toxic, and more effective triazole compounds, fluconazole and itraconazole, its use has now been limited. It now appears as an alternative drug for specific indications.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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This medication is used to control dandruff. Use of this medication may help to relieve the flaking, scaling and itching associated with dandruff. Ketoconazole is an azole antifungal that works by preventing the growth of fungus. Ketoconazole 2% shampoo is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs.

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Studies on the mechanism of the hematoporphyrin-sensitized photooxidation of 1,3-diphenylisobenzofuran in ethanol and unilamellar liposomes. The HA pattern suggests proximal load transference and bony fixation. Rather, factors are identified that may determine individual incretin secretory responses and explain some of the variations in published findings of group differences in GLP-1 responses to nutrient intake. Analgesic properties were evaluated in four rat behavioral models of pain. Biochemical characteristics of gamma gamma enolase isoenzyme and its diagnostic significance

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The presence of hepatitis B virus (HBV) DNA in serum as detected by molecular hybridization is considered the most reliable marker for the presence of complete virions and, therefore, infectivity. Nerve counts were calculated and the area of axons was measured in these nerve tissue. The differences between both growth patterns from two ages were classified into two groups according to the tooth which caused the difference: those produced by the tooth used as a standard for dental age and those produced by teeth other than that used as a dental-age standard. 145, 245-250) has been shown to have high sensitivity for measuring the sugar composition of glycoproteins.

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Glucose-induced expression of contractile smooth muscle markers in cultured cells could be partially or completely repressed by inhibitors of advanced glycation end products, L-type calcium channels, protein kinase C, Rho-kinase, actin polymerization, and myocardin-related transcription factors. Anatomical restoration of thoracolumbar spine with burst fracture

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Methods of processing of the results of field studies for evaluating the threshold and subthreshold levels of environmental factors However, the role of the fibroblast growth factor 23 in the acute but also in chronic kidney dysfunction is still a riddle that requires additional research to clarify it.

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Manipulation of the growth rate of human breast cancer cells by antiandrogen followed by chemotherapy. Since social behavior is a complicated accumulation of constructs, we performed a series of classic and refined social behavior tasks and revealed a relatively consistent pattern of enhanced pro-social behavior in hypomorphic Mecp2 (308/Y) mutant mice. Bacterial cells with multiple restriction systems for 4-bp or 6-bp target specificities are low in aggregate 4- or 6-bp palindrome counts/kb, respectively, but bacterial cells lacking exact 4-cutter enzymes generally show normal or high counts of 4-bp palindromes when compared with random control sequences of comparable nucleotide frequencies. The complications mostly results following unsafe abortion procedure done by unskilled provider with or without minimal medical knowledge in rural part of developing countries. Right Ventricular Strain in Patients with Moderate Heart Failure.

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Nutritional n-3 PUFA Deficiency Abolishes Endocannabinoid Gating of Hippocampal Long-Term Potentiation. Impact of novel histopathological factors on the outcomes of liver surgery for colorectal cancer metastases. What is the role of the podiatrist in the discovery of diabetes? The results provided evidence for mechanisms tuned to head-centered velocity-discrimination ellipses were significantly oriented away from the cardinal axes, toward the main negative diagonal. Suppression of Peritoneal Metastases by Expression of Murine Endostatin cDNA.

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The number of groups reporting clinical MRS results has increased, indicating the feasibility of performing localized MRS studies on current 1.5 T whole body MR imagers. Erratum to: Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice. Gap junction intercellular communication in carcinogenesis of endometrial cancer Recombinant DNA techniques have been used to produce multi-component vaccines by the insertion of genes into carrier organisms, such as pox viruses and attenuated salmonella, and also to produce subunit vaccines. This was true regardless of whether they were sequence replacement or sequence insertion vectors, whether they were directed toward either of the two different sites within the Hprt locus, or whether they were prepared from isogenic or nonisogenic DNA sources.

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Families affected by deafness: hospital services uptake in a multiethnic population. Adolescents with vascular frontal lesion: A neuropsychological follow up case study. The attainment of a desirable outcome when placing posterior resin composite restorations requires the clinician to have a good understanding of the benefits (as well as the limitations) posed by this material, together with a sound knowledge of placement technique. Radiation with 2 kGy resulted 7 log cycles reduction of cell count. New aminoacyl-tRNA synthetase-like protein in insecta with an essential mitochondrial function.

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