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Calutol (Bicalutamide)
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Bicalutamide

Calutol is a hormone-based chemotherapy. The NCI Drug Dictionary defines the compound as a “synthetic, nonsteroidal anti-androgen. Calutol competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors.” Calutol is used in combination with other agonists like leuprolide or goserelin for the treatment of metastatic prostate cancer. It works by blocking the normal effect of the male hormone androgen. The main type of androgens produced by the body are testosterone and dihydrotestosterone (DHT). These are formed in testes, adrenal glands and tumors themselves, and they stimulate the growth of prostate cancer cells. Calutol blocks this ability in order to stop the growth and spread of cancer.

Other names for this medication:
Bicalutamide, Casodex, Bicalox, Bicalutamida, Bicusan, Bidrostat, Caluran, Calutide, Calutol, Capro, Cosudex, Imda, Lutamidal, Probic, Zolacos,

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Calutol is used together with a luteinizing hormone releasing hormone (LHRH) analog (eg, goserelin or leuprolide) to treat stage D2 metastatic prostate cancer (cancer that has spread) in men. Calutol belongs to the group of medicines called antiandrogens. It works by blocking the effects of testosterone (a male hormone), which helps stop the growth and spread of cancer cells.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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Urethro-venous intravasation during retrograde urethrography (report of 5 cases). Molecular genotyping of M.tuberculosis is an important laboratory tool in the context of emerging drug resistant TB. We identified targets of ELF3 transcriptional repression in the oscillator, highlighting the action at the morning gene PSEUDO-RESPONSE REGULATOR9. Time intervals for real diseases, however, have distributions that in most cases are far from exponential, which leads to disagreements, both qualitative and quantitative, with the models. By contrast the BDT method produces continuous scores ranging between 0 and 1, relating to the distance between the predicted and observed residues.

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Four hundred and eighty-nine post-term women with uncomplicated pregnancies. Serum hormone levels and anthropometric characteristics in girls with hyperandrogenism. Potential routes of administration of growth factors are also considered. Effect of various treatments of porcelain surface on the bonding strength at porcelain-resin interface

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Extrafollicular (EF) ovarian tissue cocultured with isolated follicles induced ovulation, and the medium levels of PGE and PGF in such incubations were higher than those in the control. A randomized controlled study of the efficacy of six-month supplementation with concentrated fish oil rich in omega-3 polyunsaturated fatty acids in first episode schizophrenia. He was successfully weaned from an RVAD after 24 hours, and from left heart assisted circulation after 46 hours. While ctk1 mutant cells do contain phosphorylated forms of the RNA polymerase II largest subunit, these forms differ from those found in wild type cells, implicating CTK1 as a component of the physiologically significant CTD phosphorylating machinery.

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Subject to the assumption that the output of the primary visual cortex comprises Poisson neurons with known properties, our model is an ideal observer. Two proteins derived from the cell wall of Staphylococcus aureus, exhibiting apparent molecular masses of 116 kDa and 145 kDa, were found to bind to human buccal and bovine lactiferous sinus epithelial cells. Psychometric properties of the Albanian version of chewing-function questionnaire CFQ-ALB. After the middle cerebral artery of rats was occluded, changes in the content of 14 free amino acids and the activity of antioxidant enzymes in the ischemic striatum were assessed with respect to the duration of ischemia.

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The outlook for discovery of more changes in the code is favorable, and open reading frames should be compared with actual sequential analyses of protein molecules in this search. HPLC analysis of reaction products showed two new peaks, as one would expect from the cleavage of a TDP into a decapeptide and a tetrapeptide. Circulatory autonomic failure 50 years after acute poliomyelitis. To determine the influence of different clinical and periodontal parameters on the severity of gingival recession evaluated at four periods: initial, 6, 12, and 18 months of follow-up. The 1990 Medical Device Amendments to the Food and Drug Act have caused a significant change in the regulation of medical software.

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The palmate leaf form, and its variants, is present in distantly separated clades within both ferns and angiosperms. Among patients with FXS in the US and their caregivers, significant differences in health care resource utilisation and burden exist across health state utility categories. No association was found between the examined gene polymorphisms and the number of pigmented alterations in the examined study group. An Ancient Fingerprint Indicates the Common Ancestry of Rossmann-Fold Enzymes Utilizing Different Ribose-Based Cofactors.

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To investigate the risk factors of increasing AEs after BoNTA injection for idiopathic detrusor overactivity (IDO). Parenteral and enteral nutrition in cholecystitis and cholelithiasis Although response to the PAVS question of behavior last week is not correlated, this question may prompt accurate recall to the typical week question and help guide patient counseling. This review summarizes current knowledge with regard to specific hereditary retinal dystrophies in cats and gives an overview of how cats can be used as models in translational research. A positive correlation existed between increasing serum ferritin and tumour burden at presentation.

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Initial presentation and outcome of pediatric-onset mixed connective tissue disease: A French multicenter retrospective study. Targeting patients for statin therapy for the primary prevention of vascular events: what is the best approach? Enucleation cases usually require fewer traumatic surgical procedures and less supervision by the orthodontist. non-attempters) was more likely to be linked to life events in the last 6 months, the interaction between life events in the last 6 months and life events during age 0-15 years, and low social support. Comparison of cervical cytology and the polymerase chain reaction for HPV 16 to identify women with cervical disease in a general practice population.

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Celiac disease is a gluten-induced enteropathy controlled by gluten restriction. Patients were prospectively randomized within 2 hrs of intubation to receive standard endotracheal tube suctioning treatment or standard suctioning plus Mucus Shaver use until extubation. Treatment of epithelial cells with preparations of lysosomal enzymes derived from human PMNs produced similar selective effects. Rats with electrodes in the dorsal hippocampus lapped at a milk dipper and were presented a tone which predicted the delivery of a food pellet.

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Septal nuclei in the mechanisms of lateral hypothalamic self stimulation in rabbits Mepyramine duration of action of diazepam vs lorazepam duration but not cimetidine inhibited the action of histamine. The subfornical organ plays a role in a number of the effects of blood-borne angiotensin II (ANG II) including the increase in water drinking and blood pressure and the release of vasopressin from the pituitary. We have developed a system to assist in patient positioning for radiation therapy that includes an automated registration process between the reference image and target volume data before irradiation.

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Localization of the surgical bed using supine magnetic resonance and computed tomography scan fusion for planification of breast interstitial pregnancy labetalol brachytherapy. Omental dendritic cells: Ia expression and relation to macrophages. A study of proliferative activities of gastric carcinomas using monoclonal antibody 780-3 (anti P-105): preliminary report